[wroten by ZX VIAL SUPPLIES, CHINA]
As modern lifestyles continue to improve, with greater abundance and a wider variety of foods, the increasing diversity and consumption of food have naturally led to rising obesity rates—especially among women. In order to maintain a slim figure, many resort to extreme dieting for rapid weight loss, which can be extremely harmful to health.
Recently, a new generation of weight-loss products has emerged on the market, designed to block energy production and help achieve weight loss, slimming, and body shaping. Semaglutide has become the top choice for modern weight loss. However, due to limited factory production capacity, supply falls short of demand, driving up prices. This high cost has deterred many beauty-conscious individuals and fitness athletes from using it.
If you’re making semaglutide capsules manually (without a professional capsule-filling machine), here’s a detailed step-by-step guide using basic tools like a capsule filler tray, capsule counter, and capsule filter. [for your reference]
Materials Needed:
- Semaglutide API (Active Pharmaceutical Ingredient) – must be accurately weighed.
- Empty capsules (size depends on dose, usually size 2 or 3 for oral semaglutide). [https://www.zxvialsupplies.com/product-category/empty-capsules/]
- Capsule counter – to verify the number of filled capsules. [https://www.zxvialsupplies.com/product/manual-capsule-counter-60-counting-board-1/]
- Capsule filter (if needed for removing static or dust from capsules).
- Excipients (like mannitol, microcrystalline cellulose) – for proper powder flow and stability.
- Analytical balance (high precision, 0.1 mg sensitivity).
- Mortar & pestle or blender (for mixing API with excipients).
- Gloves, mask, and lab coat (to maintain sterility).
Step-by-Step Process:
1. Calculate & Weigh Semaglutide Dose
- Semaglutide is dosed in milligrams (e.g., 3 mg, 7 mg, 14 mg for oral versions).
- Use an analytical balance to weigh the exact amount (may require dilution with a filler for accuracy).
2. Mix with Excipients (if needed)
- To ensure uniform distribution, blend semaglutide with a filler (e.g., mannitol) using geometric dilution.
- Pass the mixture through a sieve to avoid clumping.
3. Prepare Capsules
- Use a capsule filling machine (manual ): [https://www.zxvialsupplies.com/product/capsule-filling-machine-200-holes/]
4. Use Capsule Counter for Verification
- After filling, pass capsules through a capsule counter to ensure the correct number.
- This helps in batch quality control.
5. Optional: Use Capsule Filter [
- If capsules have powder residue or static, a capsule filter (vibrating sieve) can clean them before packaging.
6. Quality Checks
- Weigh random capsules to ensure uniform fill weight.
- Store in airtight, light-resistant containers (semaglutide is sensitive to moisture and heat).
Important Considerations:
- Sterility: Semaglutide is a peptide; avoid contamination.
- Dosing Accuracy: Even small errors can affect efficacy.
- Regulatory Compliance: Only for licensed compounding pharmacies (semaglutide is a prescription drug).
- Oral vs. Injectable: Oral semaglutide requires special formulations (e.g., SNAC for absorption).
Below is our stop links you may need:
- Empty capsules [https://www.zxvialsupplies.com/product-category/empty-capsules/]
- Capsule counter [https://www.zxvialsupplies.com/product/manual-capsule-counter-60-counting-board-1/]
- Capsule filler machine [https://www.zxvialsupplies.com/product/capsule-filling-machine-200-holes/]
15th August, 2025